Committed to Dialysis Patients
Our commercially available products include innovative and life-saving treatments for patients with chronic kidney disease who are on dialysis.
Advancing Home Infusion Therapy
We are developing a novel therapeutic approach to managing patients with iron deficiency anemia in the rapidly expanding home infusion care setting.
Investing in the Future
Iron is an essential component of cellular function where oxygen is required or energy is produced. Our lead pipeline opportunity is a treatment for iron deficiency in acute heart failure.
Our Company Vision
Our vision is to establish a new standard of care for patients suffering with iron deficiency and iron deficiency anemia.
Iron deficiency anemia afflicts a subset of the two billion people worldwide who are nutritionally iron deficientREF. Approximately 10 million people are iron deficient in the United States, including 5 million who have iron deficiency anemia.
Our Platform Technology
Ferric Pyrophosphate Citrate (FPC)
Our innovative therapeutic was developed to replace iron loss in patients with anemia in an entirely different way. Our unique and differentiated molecule, Ferric Pyrophosphate Citrate (FPC), provides a novel mechanism of action with a physiologic approach. FPC donates iron directly to circulating transferrin making it immediately bioavailable for critical body processes, which allows the body to use the iron in a physiologic manner.
FPC is introduced to the blood
FPC donates iron directly and completely to transferrin – providing bioavailable iron for red blood cell production
FPC avoids iron sequestration by macrophages in liver and spleen
Transferrin-bound iron immediately delivered to bone marrow for hemoglobin formation
FPC delivers 100% bioavailable iron to maintain hemoglobin
FPC is introduced to the blood
FPC donates iron directly and completely to transferrin – providing bioavailable iron for for red blood cell production
FPC avoids iron sequestration by macrophages in liver and spleen
Transferrin-bound iron immediately delivered to bone marrow for hemoglobin formation
FPC delivers the desired amount of iron maintenance over time
This novel approach to the treatment of iron deficiency and anemia has the potential for application in many disease states.
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